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Pharmacokinetics:

5CL-ADB-A, also known as MDMB-4en-PINACA and MDMB-PENINACA, is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family. Its official scientific nomenclature is methyl (S)-3,3-dimethyl-2-(1-(pent-4-en-1-yl)-1H-indazole-3-carboxamido)butanoate (C20H27N3O3)[1]. .

Scientific studies:

Although no official scientific studies have been done on 5CL-ADB-A to date, a 2018 study published in Forensic Toxicology compared the potency and mechanisms of several carboxamide-like synthetic cannabinoids. These compounds, like 5CL-ADB-A, have an asymmetric carbon, derived from an amide moiety composed of amino acid derivatives. Since they are analogs of similar structures, it is assumed that these compounds behave similarly. Indeed, the study revealed that all of these synthetic cannabinoids are agonists acting on both the CB1 and CB2 cannabinoid receptors of the body's endocannabinoid system. 

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This suggests that they have a cannabimimetic effect and may be potentially more potent than THC, a  compound in cannabis, which works by acting on these same cannabinoid receptors. The study looked at AB-FUBINACA, EMB-FUBINACA, 5F-EMB-PINACA, APP-CHMINACA, and MDMB-FUBICA, all of which exhibit a similar structure to 5CL-ADB-A, suggesting that this substance may exhibit cannabimimetic effects. similar, by acting on CB1. and CB2 receptors.

Consumption patterns

This product being extremely strong, you should never put a knife tip of powder in a joint, but dilute it in e-liquid and add it drop by drop to the tank and vape it with an e-cigarette.

" If you concentrate at 1 mg/ml, following the Noid, you could kill yourself!!!

Either you potash the dilutions a little, or you find a friend who masters, or only buy products that are already ready-made.

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The new Noids are to be dosed 10 times less!!! And the result will have to be added drop by drop in classic e-liquid!!!

By concentrating at 1 mg/ml, if it is 5F-ADB or an ultra potent Noid, 1 single drop will give an ultra concentrated product which will initiate an overdose on the first hit (and worse if affinity)..

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Vaping

Terpenes and CBD can be added to the C-liquid to better control the effect.

" I vape about 2 ml every 3 4 days liquid containing 5f-abp terpene lavender for the anti-stress and relaxing side and about 300 mg of cbd for 15 ml of juice... it reduces and stabilizes these suicidal thoughts »

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Dosage

" I made it yesterday like this:

0.5 liters of Propylene Glycol, in which I cold mix one gram of 5F-ADB. So I got a "suspension" at 2 mg/ml.

I put my caramel thermometer (yes, a real pastry chef) in the beaker and I put this beaker on a hot plate. When the thermometer reached 65° Celsius I removed the beaker to dip its Q in cold water to stop the rise in temperature while mixing with a silicone kitchen whisk. There I thus obtained a solution with 2 mg/ml.

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I then covered with cling film then I put the beaker on a radiator all night, the next day the dissolution was perfect and ready to use, but I'm not that stupid, at 2 mg/ml I know that I'm going to stay there so adding 200 ml of glycerin and 300 ml of neutral propylene, I end up with a magnificent dissolution at 20 degrees Celsius (so I don't bleach the glycerin.. source: my personal experiences) which is titrated to 1mg/ml.

Here I know that it will not hurt me more than I wish but I also know that the product is wasted because on my person, the effect will be exactly the same at 0.5 mg/ml.

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So I give a liter of base 70% propylene glycol / 30% glycerin flavored mint / eucalyptus (each to their own tastes) nicotine at 12 mg / ml. I would point out that the use of nicotine depends on only one thing: everyone's choice!

And there that already makes me a two-litre can; thinking includes profitability thinking and :thanks:also includes the dangerousness of 5F-ADB thank you-1

So this morning I have in my e-cig a mint/eucalyptus liquid with 6 mg/ml of nicotine and 0.5 mg/ml of 5F-ADB.

So basically, and cross me when I say I'm a regular at this particular noid; I take my big wank in the morning because with 0.5 mg/ml it's not the time to be a novice, do we understand each other well?

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The desired effects

" I unpack, I put two drops of the product in the tank of my vape full of e-liquid, I use terpenes from cali-terpenes as an aroma, I mix well and let it sit for 10-15 min.

A mini hit of social security, I wait 25 minutes. I eat, then sit down. I prepare a film, some music and I get comfortable on the couch.

The puff didn't do anything to me, so I take two good big puffs and wait.

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t+5: It starts all of a sudden, feeling of lightness, of intense well-being in the whole body. I realize that my muscles were knotted and sore from the sport of the day before and I feel them "working", relaxing very strange and pleasant feeling... I see my reflection in the TV and I have a joker smile taped on the face, big feeling of euphoria. Eyes heavy, very red, no feeling of heaviness. I'm in heaven, never loved so much, so fast, so strong, so good, I'm in love, I found MY magic product!

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t+10: Solo giggles, the music is going well, I'm rewatching a stand-up comedy that I've already seen 10 times but here, I'm in it, I understand nuances that I had never captured, my brain goes fast a bit like under certain shrooms. Good thoughts, I think back to old friends, my family, all those who left too soon... But not sad, nostalgic but happy to have known them.. I see things with a lot of empathy... I forgive ...I feel like I get the best effects from weed, shrooms and ecta ​​at the same time.

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t+45: It continues, it even goes up very gradually, very slowly, it's GOOD!!! But first "ohoh sad". I "catch myself" stopping the vape three or 4 times with the C-liquid tank, mechanically.. So I change and vape my E-liquid. I'm fine, I tell myself that I'm going to take another dose when this one has evaporated and after bedtime.

T+ 1h: It's starting to go down, I'm on vacation tomorrow but it's late..

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" For the 5F-ADB, it's a Pinaca, so rather high effects. The descent makes me close my eyes, if I don't re-drop. »

The risks of consumption

The side effects

" The next day, rest day, I was planning to tidy up at home in the morning. "But it's already done"... And I tell myself that this is the opportunity to test just a puff and to be able to study this a little more amazing product...

One puff.. Nothing... So I dose again well, I estimate (quite randomly..) that I am at 20% of my tolerance and that just a little now is good... 5 or 6 puffs ... Very good experience, in line with the first take, except that here I let the product go down. Almost no after buzz or fatigue. If I get to that point with weed at 11 a.m. my day is just over. There I am totally fresh.

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I eat well and I dose again a few moments later without really realizing it... But then I bottle up on the thing with unconscious confidence... The rest is two days of loss of bearings and psychoses (I don't never had effects even approaching this and this intensity). Loss of consciousness, moments of euphoria increasingly mixed with moments of depression, suicidal thoughts, black outs... Do you want some here...

Very strange moments, very dark little halus, the edges of my field of vision are black, dark and moving and...they whisper.. I hear noises, I see cockroaches running (I hate these bugs and I sell my direct apartment if there are any!)

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" I consumed very very little of the order of 0.01g in a cigarette by habit and having not consumed for 15 days.

I don't remember, just the memory of having had a heart attack, my heart racing and I couldn't breathe. I saw like a clock and in the center a kind of yellow square that made me breathe except that I couldn't stop on it to breathe... in short, the trip from hell. 

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I fell from my chair in bottles in my bars and I vomited everywhere (I specify that at this time I was screaming to death I was crying I was making a mess in my apartment) I found my chair on my table bass when I wake up and vomit everywhere as well as a new half-consumed ter!!! This stuff disconnects things in the brain. It's shit. In short, at that moment I was dead, big blackout, except that it was the gendarmes who came to wake me up in the middle of the night, I was on the ground like shit..

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" Then after a good month of drinking, the bottle came to an end and I started to dilute it even more.

Towards the end of my last tank mix, I had a pretty strong tachycardia that bothered me when I vaped and then a big constant heart gene.neutral

Then once taking more than I thought (probably badly diluted) I thought I was having a small myocardial infarction (heart attack for friends), at the time I was convinced, given the pain, that my heart had returned to my body

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Tolerance, habituation, dependence

This product has a rapidly rising tolerance.

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" I started with a tank almost full of nicotine e-liquid (7mg I think) adding 5F-ADB drop by drop until I noticed an effect.

Vaping all afternoon I end up with a half 5F-ADB half base mix. The effects are felt well, big, very fast rise with an effect close to a very strong sativa.

My tolerance rising quickly, I very quickly ended up putting my pure C-liquid in my tank.

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